Review Series: May 16, 2019

Human Neutrophils

Neutrophils are critical to innate immunity and serve as the major phagocytic defense against invading organisms. This Review Series introduced by Drs. Berliner and Coates focuses on novel insights into the “secret lives” of neutrophils, which have critical roles in modulating hematopoiesis and the hematopoietic niche, influencing inflammatory responses, regulating the tumor microenvironment, and promoting thrombosis.


Listen as Drs. Nancy Berliner and Mary C. Dinauer discuss highlights of this review series.


Review Series Articles:

Introduction to a review series on human neutrophils
Nancy Berliner and Thomas D. Coates



Neutrophils as regulators of the hematopoietic niche
Itziar Cossío, Daniel Lucas and Andrés Hidalgo



Neutrophil plasticity in the tumor microenvironment
Morgan A. Giese, Laurel E. Hind and Anna Huttenlocher


Cross talk between neutrophils and the microbiota
Dachuan Zhang and Paul S. Frenette


Neutrophils and NETs in modulating acute and chronic inflammation
Fernanda V. S. Castanheira and Paul Kubes


Neutrophils: back in the thrombosis spotlight
Denis F. Noubouossie, Brandi N. Reeves, Brian D. Strahl and Nigel S. Key




See a full listing of the Blood Review Series here