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Review Series - April 23, 2015

Introduced by Dr. Margaret Goodell, this review series describes the state of our knowledge of the ontogeny and regulation of hematopoietic stem cells (HSCs) and the role of the bone marrow niche in their development. Other articles discuss xenograft models for studying normal and malignant stem cells and the current state of the art of generation of stem cells from somatic and pluripotent stem cell sources.

 

 

 

Making sense of hematopoietic stem cell niches
Philip E. Boulais and Paul S. Frenette

 

Xenograft models for normal and malignant stem cells
Susumu Goyama, Mark Wunderlich, and James C. Mulloy

 

 


Blood Journal Review Series