Review Series - June 25, 2015

Introduced by Dr. Jean Soulier and Dr. Jorge Cortes, this review series highlights recent advances in the field of acute lymphoblastic leukemia (ALL) and their impact on developmental therapeutics. They address molecular precision diagnostics, minimal residual disease detection, genetic variation in childhood ALL, and the newest immunotherapeutic approaches.




Inherited genetic variation in childhood acute lymphoblastic leukemia
Takaya Moriyama, Mary V. Relling, and Jun J. Yang


Minimal residual disease diagnostics in acute lymphoblastic leukemia: need for sensitive, fast, and standarized technologies
Jacques J. M. van Dongen, Vincent H. J. van der Velden, Monika Brüggemann, and Alberto Orfao


Monoclonal antibodies in acute lymphoblastic leukemia
Elias Jabbour, Susan O’Brien, Farhad Ravandi, and Hagop Kantarjian