Table 1.

Baseline characteristics and prior treatment history

CharacteristicAll treated (N = 85)Lenalidomide refractory (n = 51)
Age, median (range), y66 (38-85)66 (38-85)
ECOG performance status
 0-178 (92)47 (92)
 27 (8)4 (8)
No. of prior lines
 Median (range)2 (1-4)2 (1-4)
 120 (24)6 (12)
 240 (47)26 (51)
 323 (27)18 (35)
 >32 (2)1 (2)
Prior ASCT62 (73)33 (65)
Prior bortezomib85 (100)51 (100)
Prior IMiD85 (100)51 (100)
 Lenalidomide81 (95)51 (100)
 Pomalidomide13 (15)9 (18)
 Thalidomide21 (25)11 (22)
Refractory to:*
 Lenalidomide51 (60)51 (100)
 Pomalidomide11 (13)9 (18)
 Bortezomib26 (31)21 (41)
 PI + IMiD25 (29)22 (43)
  • Unless otherwise noted, all data are n (%).

  • * Refractoriness was based on most recent prior medication.