Table 2.

Response

ParameterOverall, n (%)Decitabine, n (%)Azacitidine, n (%)P
Morphologic response, N1097039
 CR40 (37)26 (37)14 (36)
 mCR8 (7)6 (9)2 (5)
 HI20 (18)17 (24)3 (8)
 Overall68 (62)49 (70)19 (49).03
Transfusion response, N573819
 RBC11/46 (24)8/29 (28)3/17 (18)
 Platelets3/5 (60)3/4 (75)0/1
 RBC + Platelets1/6 (17)1/5 (20)0/1
 Overall15 (26)12 (32)3 (16).2
Cytogenetic response, N442816
 Complete8 (18)7 (25)1 (6)
 Partial13 (30)10 (36)3 (19)
 Overall21 (48)17 (61)4 (25).02
Morphologic response (BM blasts ≥5%), N322111
 CR14 (44)12 (57)2 (18)
 mCR8 (25)6 (29)2 (18)
 HI3 (9)3 (14)0
 Overall25 (78)21 (100)4 (36)<.001
Hematologic response (BM blasts <5%), N724527
 ≥1 lineage29 (40)16 (36)13 (48)
 All lineages17 (24)10 (22)7 (26)
  • HI, hematologic improvement; RBC, red blood cell.