Table 3.

Multipredictor models of laboratory predictors of grade ≥2A bleeding, taking into account within-person correlation

PredictorModel 1*Model 2
OR95% CIPOR95% CIP
Stratum<.001<.001
 ALLO1.00Ref.1.00Ref.
 AUTO0.440.34-0.56<.0010.380.26-0.55<.001
 CHEMO0.550.43-0.71<.0010.550.39-0.77<.001
Platelet count, ×109/L<.001.55
 1-52.961.93-4.54<.0011.790.86-3.75.12
 6-102.021.41-2.87<.0011.620.98-2.68.06
 11-152.341.65-3.33<.0011.610.95-2.72.08
 16-202.211.56-3.13<.0011.620.94-2.78.08
 21-251.961.37-2.79<.0011.520.91-2.54.11
 26-301.891.33-2.68<.0011.861.12-3.09.02
 31-352.061.45-2.94<.0011.680.96-2.94.07
 36-401.821.26-2.63.0011.500.86-2.61.16
 41-451.911.33-2.74<.0011.570.89-2.75.12
 46-502.011.33-3.04<.0011.810.97-3.37.06
 51-552.101.38-3.19<.0011.760.96-3.23.07
 56-601.821.18-2.80.011.560.78-3.12.21
 61-651.250.74-2.10.410.910.41-2.01.82
 66-702.541.60-4.02<.0012.280.97-5.34.06
 71-751.640.91-2.98.100.960.41-2.25.93
 76-801.670.91-3.04.101.460.60-3.55.40
 81+1.00Ref.1.00Ref.
Hematocrit, %.02.35
 ≤251.201.03-1.39.021.080.84-1.38.56
 26-291.060.94-1.19.360.930.74-1.18.57
 >291.00Ref.1.00Ref.
aPTT.04
 ≤301.00Ref.
 31-501.170.90-1.52.24
 >501.901.24-2.91.003
INR.01
 ≤1.21.00Ref.
 1.3-1.51.351.06-1.71.01
 >1.51.791.28-2.52<.001
  • OR, odds ratio; Ref., reference.

  • * Grade ≥2A bleeding days/total days = 2403/15 979 = 15%.

  • Grade ≥2A bleeding days/total days = 612/3,604 = 17%.