Table 1.

Patient characteristics (N = 211)

VariableTac/SirTac/MtxP value
Number of patients104107
Underwent transplantation104 (100)107 (100)
Age, median, y (range)45 (19-59)41 (13-58).079
Male sex53 (51)48 (45).41
Primary malignancy.19
 Acute myelogenous leukemia46 (44)40 (37)
 Acute lymphoblastic leukemia38 (37)53 (50)
 Chronic myelogenous leukemia8 (8)9 (8)
 Myelodysplastic syndrome11 (11)5 (5)
 Acute biphenotypic leukemia1 (1)0 (0)
Disease status at transplantation
 Acute myelogenous leukemia.58
  1st complete remission37 (80)34 (85)
  2nd complete remission9 (20)6 (15)
 Acute lymphoblastic leukemia.86
  1st complete remission31 (82)44 (83)
  2nd complete remission7 (18)9 (17)
 Chronic myelogenous leukemia.60
  Chronic phase7 (88)7 (78)
  Accelerated phase1 (13)2 (22)
 Acute biphenotypic leukemia
  1st complete remission1
Karnofsky score.97
 90-100%72 (69)77 (72)
 <90%32 (31)30 (28)
Recipient-donor CMV status.028
 +/+41 (39)33 (31)
 +/−21 (20)34 (32)
 −/+9 (9)18 (17)
 −/−27 (26)17 (16)
 Missing6 (6)5 (5)
Recipient CMV status.66
 +66 (63)71 (66)
 −38 (37)36 (34)
Donor-recipient sex match.77
 Female-male29 (28)30 (28)
Conditioning regimen
 Cyclophosphamide/total body irradiation85 (82)84 (79).56
 Etoposide/total body irradiation19 (18)23 (22)