Table 18

Cytogenetic abnormalities sufficient to diagnose AML with myelodysplasia-related changes when ≥20% PB or BM blasts are present and prior therapy has been excluded

Cytogenetic abnormalities
Complex karyotype (3 or more abnormalities)
Unbalanced abnormalities
 −7/del(7q)
 del(5q)/t(5q)
 i(17q)/t(17p)
 −13/del(13q)
 del(11q)
 del(12p)/t(12p)
 idic(X)(q13)
Balanced abnormalities
 t(11;16)(q23.3;p13.3)
 t(3;21)(q26.2;q22.1)
 t(1;3)(p36.3;q21.2)
 t(2;11)(p21;q23.3)
 t(5;12)(q32;p13.2)
 t(5;7)(q32;q11.2)
 t(5;17)(q32;p13.2)
 t(5;10)(q32;q21.2)
 t(3;5)(q25.3;q35.1)