Table 17

Classification of myeloid neoplasms with germ line predisposition

Myeloid neoplasm classification
Myeloid neoplasms with germ line predisposition without a preexisting disorder or organ dysfunction
 AML with germ line CEBPA mutation
 Myeloid neoplasms with germ line DDX41 mutation*
Myeloid neoplasms with germ line predisposition and preexisting platelet disorders
 Myeloid neoplasms with germ line RUNX1 mutation*
 Myeloid neoplasms with germ line ANKRD26 mutation*
 Myeloid neoplasms with germ line ETV6 mutation*
Myeloid neoplasms with germ line predisposition and other organ dysfunction
 Myeloid neoplasms with germ line GATA2 mutation
 Myeloid neoplasms associated with BM failure syndromes
 Myeloid neoplasms associated with telomere biology disorders
 JMML associated with neurofibromatosis, Noonan syndrome or
 Noonan syndrome-like disorders
 Myeloid neoplasms associated with Down syndrome*
  • * Lymphoid neoplasms also reported.