Table 2

Immunohistochemistry features of SMZL and other small B-cell lymphomas

SMZLLPLSDRPLHCL-vHCLEMZL/ NMZLCLLMCLFL
CD20++++++−/+++
CD79a+++++++++
CD5−/+−/+−/+−/+++
CD21−/+
CD23−/+−/+−/++−/+
BCL1−/+++
DBA44+/−+++−/+
Annexin A1+
CD103+/−+
CD123+
IRTA1+/−
IgM+++++++++
IgD+/−−/+++−/++++
CD10**+/−
BCL6−/+−/++
CD43−/+−/+++
SOX11+
LEF1+−/+
  • –, <25% of cases; –/+, 25%-50% of cases; +/–, 50%-75% of cases; +, >75% of cases.

  • FL, follicular lymphoma; NMZL, nodal marginal zone lymphoma; SDRPL, splenic diffuse red pulp lymphoma.

  • * Sporadic cases reported.