Table 1

Patient and transplantation characteristics:

Characteristic Total =150 patientsHaplo transplant (n = 69)CB transplant (n = 81)P value
Patients Age years (median) [range]44 (19-68)47 (18-66)
Patients sexns
Male39 (57)46 (57)
Female30 (43)35 (43)
Disease type
AML3 (4)37 (46)<0.0001
ALL1 (1)14 (17)<0.0001
NHL24 (35)14 (17)ns
HL30 (43)2 (2)<0.0001
MM4 (6)2 (2)ns
CLL5 (7)4 (5)ns
CML01 (1)ns
MDS/ MPS2 (3)7 (9)ns
Status of disease
CR37 (54)56 (69)ns
PR/SD24 (35)12 (15)0.04
PD8 (11)13 (16)ns
Donor type
Sibiling32 (46)
Parent18 (26)
Child18 (26)
cousin1 (2)
Donor/recipient sex mis-match34 (49)56 (69)ns
ABO incompatibility24560.02
Conditioning regimen
Flu 5+Cy 1+ TBI075 (93)
Flu 5+Cy 2+ TBI69 (100)6 (7)
Stem cell source
Peripheral Blood19 (28)
Bone Marrow50 (72)
Stem cell dose median [range] CD34+ x 106/kg3,96 (0,8-14)0,9 (0,08-1,28)
GvHD prophylaxis
CSA+MMF69 (100)81 (100)ns
Cy post transplant69 (100)0
Days with ANC< 500 x 109/l20 (14-39)22 (6-67)ns
Days with platelets<20 x 109/l29 (14-50)41 (18-80)ns