Table 3

Symptoms of infusion-related reactions and other drug-related AEs, listed by frequency, experienced by 3 or more patients during infusion and within 24 hours after completion of infusion (N = 21)

AEn%
Patients with at least 1 AE1886
Hypotension*1152
Pyrexia1048
Nausea*943
Vomiting*838
Chills*629
Asthenia629
Flushing314
Headache314
Larynx irritation314
  • * One patient experienced grade 3 hypotension, nausea, vomiting, and dizziness that resulted in the dosage being modified. Other grade 3 events were observed in a mantle cell lymphoma patient who experienced tumor lysis syndrome; events included asthenia, chills, dyspnea, headache, hyperkalemia, hyperthermia, leukopenia, and thrombocytopenia. No grade 4 infusion-related events were observed.