Table 3

Grade ≥3 AEs with ≥3% incidence

Adverse event*TN ≥65 years (n = 31)R/R (n = 101)Total (n = 132)
Hypertension7 (23)20 (20)27 (20)
Pneumonia2 (6)25 (25)27 (20)
Neutropenia1 (3)18 (18)19 (14)
Thrombocytopenia1 (3)10 (10)11 (8)
Atrial fibrillation2 (6)6 (6)8 (6)
Diarrhea5 (16)3 (3)8 (6)
Fatigue1 (3)5 (5)7 (5)
Sepsis07 (7)6 (5)
Cellulitis05 (5)5 (4)
Dehydration05 (5)5 (4)
Febrile neutropenia05 (5)5 (4)
Hyperglycemia1 (3)4 (4)5 (4)
Hypokalemia1 (3)4 (4)5 (4)
Sinusitis05 (5)5 (4)
Bacteremia04 (4)4 (3)
Decreased appetite04 (4)4 (3)
Decreased lymphocyte count1 (3)3 (3)4 (3)
Increased lymphocyte count04 (4)4 (3)
Leukocytosis04 (4)4 (3)
Lymphocytosis04 (4)4 (3)
Syncope1 (3)3 (3)4 (3)
  • Values are n (%).

  • * AEs are listed by preferred term.