Table 5

Molecular response among patients achieving complete cytogenetic response

ResponseImatinib resistantImatinib intolerantTotal
Cumulative response*
    Patients in subgroup analysis552378
Reason for exclusion from analysis
    No assessment702191
    Did not achieve complete cytogenetic response7544119
  • * Major molecular response = ≥ 3 log reduction from standardized baseline Bcr-Abl:Abl ratio. Complete molecular response = undetectable Bcr-Abl, with a sensitivity of ≥ 5 log. Molecular response was not assessed according to the International Scale.

  • Because of logistical constraints, 4 countries (China, India, Russia, and South Africa) did not evaluate molecular response.