Table 3

Additive total score and related rate of OS and PFS at 3 years

Additive total scorePatient statusNo. of patients (%)% (95% CI)Cumulative incidence at 12 mo, %
OSPFSTreatment discontinuationGrade 3-4 nonhematologic AEs
0Fit340 (39)84 (78-89)48 (41-56)1622
1Intermediate-fitness269 (31)76 (67-82)41 (32-49)2126
≥2Frail260 (30)57 (45-68)33 (25-41)3134
  • In the univariate Cox model, the Harrell C index = 0.6608 and the AIC = 1766.077. In the multivariate Cox model, the Harrell C index = 0.7092 and the AIC = 1743.353.