Table 1.

Success rate of human thymopoiesis according to mouse strain and conditioning

N (mice)NOD/SCID RTNOD/SCID RT + TM-β1Rag2−/−γc−/− mice RT
DP in thymus (no.)5224
Success rate (%)18566
  • Comparison of thymus repopulation frequency between irradiated NOD/SCID mice (RT), irradiated NOD/SCID mice pretreated with injection of TM-β1 (RT + TM-β1), and irradiated Rag2−/−γc−/− mice (RT). Of each group, the total number of mice and number/percentage of mice having DP (≥ 5%) in their thymi are shown.