Table 2.

Raised serum Epo in anemic Stat5a−/−5b−/− mice

Mouse no.GenotypeHematocrit
(%)
Hemoglobin
(g/dL)
Serum Epo (mU/mL)
4355a−/−5b−/− 239.5360
4315a−/−5b−/− 208.4720
1815a−/−5b−/− 16ND4 000
4365a−/−5b−/− 41.012 000
5735a−/−5b−/− 3611.9< 100
5755a−/−5b−/− 4513.6< 100
449Wild-type4517.9< 100
557Wild-type4615< 100
  • Epo was measured using a sandwich ELISA in several anemic and nonanemic Stat5a−/−5b−/− mice and in wild-type littermate controls. Serum Epo below 100 mU/mL could not be reliably measured by this assay. Normal mouse serum Epo is in the range of 10 to 20 mU/mL.22

  • ND indicates not done.