Table 6.

Association of donor T-cell chimerism with rejection and acute graft-versus-host disease

Percent donor PB T-cell chimerism as a categorical variable
% donor T cells on day 28No. rejection/no. at risk (%)No. GVHD/no. at risk (%)
0-255/6 (83%)0/1 (0%)
26-503/11 (27%)2/8 (25%)
51-751/11 (9%)5/10 (50%)
76-1000/16 (0%)9/15 (63%)
Pvalue.00016-150 .326-150
  • GVHD indicates graft-versus-host disease; PB, peripheral blood.

  • Analysis of GVHD restricted to 35 patients with sustained engraftment and without GVHD before day 28. Patient UL627 was excluded from analysis because of lack of DNA polymorphism.

  • F6-150 P value obtained from Fisher's exact test.