Table 1.

Digestion of IL-8 by gelatinase B and aminoterminal sequence analysis

Aminoterminal sequencesBefore digestion (%)*After digestion (%)*
Natural IL-8
 IL-8(-2-77)EGAVLPR …100
 IL-8(1-77)AVLPRSA …350
 IL-8(6-77)SAKELRCQC …5560
 IL-8(7-77)AKELRCQC …040
Recombinant IL-8
 IL-8(1-77)AVLPRSA …1000
 IL-8(7-77)AKELRCQC …0100
  • *  Relative amounts were determined by aminoterminal sequence analysis.