Table 5.

Expression of MLL-AF4 Fusion Transcripts in Normal Hematopoietic Tissues

Tissue NMLL-AF4+
Standard PCRNested PCR
N % Total N% Total
Infant BM 6 0 0 1 17
Fetal BM 16 0 0 4 25
Fetal liver 13 0 05 38
Pediatric ALL remission BM 44 0 0 00
  • Infant BM was obtained from an 11-month-old boy.MLL-AF4 + fetal BM were: FBM 4, 19 weeks gestational age; FBM 6, 20 weeks gestational age; FBM 7, 21 weeks gestational age; FBM 11, 18 weeks. MLL-AF4 +fetal livers were: FL1, 16 weeks gestational age; FL14, 19 weeks gestational age; FL10, 20 weeks gestational age; FL12, 21 weeks gestational age, FL13, 22 weeks gestational age. Remission BM specimens were day 28 aspirate samples from pediatric ALL patients on CCG-1952 standard-risk ALL study.