Table 1.

Characteristics of 20 Patients Who Showed Conversion to PCR+ and Subsequent Hematologic Relapse

Patient No. Age/Sex PML Break TypeMaintenance First Molecular CR Duration (mo)-150Time From PCR+ to Hematologic Relapse (mo)
1. 53/F L None 3 3
2. 36/F SNone 3 6
3. 38/M L CHT-151 5 3
4. 35/F S CHT + ATRA 5 2
5.43/M L None 4 2
6. 54/M LCHT + ATRA 2 14
7. 44/M S CHT + ATRA8 9
8. 43/M L ATRA 5 1
9. 25/MS None 3 1
10. 35/M S CHT + ATRA3 4
11. 62/M L CHT 10 4
12.20/M L None 1 4
13. 10/M L CHT9 2
14. 26/F L CHT 4 3
15. 46/FS ATRA 9 8
16. 29/M L ATRA 2 3
17. 13/M L ATRA 4 1
18. 13/F LNone 5 3
19. 44/F S None 4 1
20. 37/M S None 4 1
  • Abbreviations: L, long type; S, short type.

  • F0-150 Months after consolidation.

  • F0-151 CHT, chemotherapy including methotrexate and 6-mercaptopurine.