Table 2.

Expression of c-kit and Flt3 Receptors on Murine and Human Cell Lines

c-kitFlt3
Myeloid Few positive Mostly positive*
Monocytic Few About 50%
Erythroid MostFew
Megakaryocytic Most Few
Mast cell AllNone
Lymphoid
 Pro-B None Most
 Pre-BNone Most*
 B None Few
 T None Few
 Mature NK ND None
Lymphomas None About 25%
Myeloma None None
  • Results tabulated from a large number of reports. For individual references, see the sections of this report detailing the expression patterns for each of these receptors.

  • Abbreviation: ND, not determined.

  • * Different expression patterns have been reported on mouse versus human cells; see text for details.