Table 2.

CTL Activity and Cell Phenotype After IVS

Patient No.ActivityLU20/106 CellsCell Subsets%CD8+ Lymphocytes
ConditionvCP300 + IL7ConditionOKT3vCP300 + IL7
OKT3PBL
4Anti-Env45CD3+CD8+ 557972
Anti-Gag627CD8+CD45RA+ 334140
Anti-Pol1759CD8+CD45RO+ 253329
Anti-Nef1768CD8+HLA-DR+ 322932
CD8+CD25+ 13314
CD8+CD38+ 277961
CD3CD56+16+ 71320
8Anti-Env1316CD3+CD8+ 348482
Anti-Gag1847CD8+CD45RA+ 245239
Anti-Pol2364CD8+CD45RO+ 154238
Anti-Nef2162CD8+HLA-DR+ 163852
CD8+CD25+ 1225
CD8+CD38+ 97755
CD3CD56+16+ 1077
9Anti-Env860CD3+CD8+ 318378
Anti-Gag248CD8+CD45RA+ 136944
Anti-Pol722CD8+CD45RO+ 153448
Anti-Nef546CD8+HLA-DR+ 182873
CD8+CD25+ 1910
CD8+CD38+ 98364
CD3CD56+16+ 1775
10Anti-Env620CD3+CD8+ 407164
Anti-Gag728CD8+CD45RA+ 313710
Anti-Pol194CD8+CD45RO+ 111530
Anti-Nef3368CD8+HLA-DR+ 244134
CD8+CD25+ 1513
CD8+CD38+ 194642
CD3CD56+16+ 31124
  • Anti-HIV reactivities are reported as LU20 /106 cells, subtracting the anti-vaccinia background.