Table 2.

Factor-Dependent and -Independent Colonies Formed by Fetal Liver Cells Infected With Wild-Type and Mutant hβc Subunits

RufNeo ConstructAdditionsColony types (%)Colonies Examined
GEoMastMGMMixBFU-EBlast
hβcIL-3, GM, Epo1214393384103
IL-3, GM, Epo, G4181836382655109
FIΔEpo342436680
17453884
V449EEpo91122617293369
1387302018561
I374NEpo47915173
1891093
  • Data are a combination of two separate experiments. Colony types were determined at day 7 of culture.

  • Abbreviations: G, neutrophilic granulocyte; Eo, eosinophil; Mast, mast cell; M, macrophage; GM, granulocyte-macrophage; Mix, mixed myeloid/erythroid; BFU-E, erythroid burst-forming unit; Blast, blast cell; GM, GM-CSF.