Table 1.

Differential Cell Counts of Factor-Dependent and Factor-Independent Fetal Liver Cells

RufNeo ConstructAdditionsCell Type (%)
EosMastNeutMKMErythMyelBlast
Day 7
hβcIL-3, GM, Epo0.62.932.80.627.04.626.45.2
IL3, GM, Epo, G4181.045.50.318.39.320.65.0
FIΔEpo67.328.72.71.3
69.730.3
V449EEpo0.31.347.80.34.310.032.63.3
2.00.748.80.70.72.339.95.0
I374NEpo4.092.93.2
11.288.8
Day 21
hβcIL-3, GM, Epo9.041.041.09.0
IL-3, GM, Epo, G4181.00.379.313.36.0
FIΔEpo99.30.7
100.0
V449EEpo8.36.01.372.012.3
0.72.793.33.3
I374NEpo100.0
100.0
  • Data are representative of three separate experiments.

  • Abbreviations: Eos, eosinophils; Mast, mast cells; Neut, neutrophils; MK, megakaryocytes; M, monocytes/macrophages; Eryth, erythroid cells; Myel, promyelocytes/myelocytes; Blast, blast cells; GM, GM-CSF.