Table 3.

CFU Assay (Day 14)

Patient No. 4Normal Values3-150
CFU-GMBFU-ECFU-MegaMedian (range)
CFU-GMBFU-ECFU-Mega
Control0000 (0-3)0 (0-2)0 (0)
TPO3-151 2000 (0-1)0 (0-3)11 (4-40)
G-CSF,† GM-CSF,† IL-3,† SCF,† EPO3-151 428507nd3-152 125 (68-240)180 (91-431)nd3-152
  • Colony numbers are based upon 105 BM-MNC. Data represent the mean of duplicates.

  • F3-150 Obtained in our laboratory from 12 healthy individuals, using the same experimental conditions.

  • F3-151 10 ng/mL each, except for EPO (1 U/mL).

  • F3-152 Counting Mega-colonies was not possible in dishes with “maximum stimulation” because of the high numbers of colonies.