Table 1

Embryonic lethality of due to deletion of Mfrn1

Embryos/pups≤ E9.5 (n = 37)≥ E11.5 (n = 41)Newborn (n = 64)
Mfrn1+/+101020
Mfrn1+/−192244
Mfrn1−/−800
Not determined (necrotic embryos)090
  • Mice (Mfrn1+/−) heterozygous for a Mfrn1 deletion were intercrossed and the progeny were genotyped.