Table 4

Definitions of time to and duration of response, and the time to initial and peak response for different ITP treatments*

Time to responseFrom start of treatment until either complete response or response
Duration of responseTime from complete response or response until loss of complete response or response Measured as the proportion of the cumulative time spent in complete response or response during the period under examination as well as the total time observed from which the proportion is derived
Expected time to responseTreatment typeInitial response, daysPeak response, days
Anti-D1-33-7
Azathioprine30-9030-180
Danazol14-9028-180
Dexamethasone2-144-28
Eltrombopag7-2814-90
IVIg1-32-7
Prednisone4-147-28
Rituximab7-5614-180
Romiplostim5-1414-60
Splenectomy1-567-56
Vinblastine7-147-42
Vincristine7-147-42
  • * Adapted from the International Working Group.7