Table 1

HCMV VR1814-induced and -repressed secretome factors* in infected HUVECs

ProteinMock secretome average intensity ± SDInfected secretome average intensity ± SDFold changeP
RANTES1591 ± 21548982 ± 65930.8.0000
MCP-21625 ± 18624136 ± 577714.8.0004
I-30990 ± 131150 ± 35212.8.0020
MIP-3α5815 ± 36947202 ± 65718.1.0000
IL-66769 ± 39543424 ± 43396.4.0000
IP-101261 ± 1187451 ± 6305.9.0000
GCP-21471 ± 886824 ± 13014.6.0002
MIP-1β982 ± 423580 ± 9473.6.0043
MCP-38184 ± 96328152 ± 39623.4.0001
MPIF-15812 ± 60219259 ± 10943.3.0000
GM-CSF1422 ± 1024384 ± 5073.1.0000
I-TAC2436 ± 2197626 ± 9963.1.0003
Osteoprotegerin179 ± 34555 ± 1063.1.0030
ICAM-1544 ± 281636 ± 2093.0.0001
GRO-α1443 ± 1493985 ± 3542.8.0001
MMP-917 ± 843 ± 62.5.0167
MIP-1α1680 ± 1394045 ± 6402.4.0005
Sglec5123 ± 56295 ± 532.4.0390
TIMP4110 ± 49218 ± 342.0.0155
Axl779 ± 1201648 ± 3512.1.0171
PDGF AA10368 ± 121519024 ± 46681.8.0278
IL-8865 ± 631507 ± 1121.7.0019
CD14535 ± 85883 ± 441.6.0030
EGF1375 ± 892246 ± 4251.6.0179
CXCL162075 ± 653365 ± 6601.6.0418
TNFα1309 ± 991923 ± 1571.5.0025
VE-cadherin82 ± 3125 ± 141.5.0050
PDGF AB3396 ± 2754703 ± 5881.4.0066
b-NGF307 ± 56332 ± 121.1.0390
MIF2280 ± 2831423 ± 2280.62.0019
Tie-1470 ± 73223 ± 360.47.0019
Endoglin1053 ± 208463 ± 1070.44.0024
TRAIL R33134 ± 195848 ± 130.27.0000
TECK133 ± 1022 ± 130.16.0000
PECAM-12470 ± 82354 ± 130.15.0000
  • * Factor values (in arbitrary units) were determined by RayBiotech protein array analysis. Averages ± SD are shown from mock and infected intensity values.