Table 3

Number of cases and crude incidence rate (IR) per 100 000 for myeloid malignancies diagnosed in 2000-2002 archived in 44 European CRs by sex and morphologic type

HAEMACARE groupingsICD-O-3 codeICD-O-3 descriptionNo. of casesTotalMalesFemales
IR95% CIIR95% CIIR95% CI
Acute myeloid leukemia*81073.62(3.54-3.70)3.90(3.78-4.02)3.35(3.25-3.46)
    Subgroup 19840Acute erythroid leukemia75453.37(3.29-3.45)3.64(3.53-3.76)3.11(3.01-3.21)
9861AML, NOS
9867Acute myelomonocytic leukemia
9870Acute basophilic leukemia
9872AML, minimal differentiation
9873AML without maturation
9874AML with maturation
9891Acute monocytic leukemia
9910Acute megakaryoblastic leukemia
9930Myeloid sarcoma
    Subgroup 29866Acute promyelocytic leukemia t(15; 17) (q22; q11-12)3110.14(0.12-0.16)0.13(0.11-0.15)0.15(0.13-0.17)
9871AML with abnormal marrow eosinophils
9896AML, t(8,21) (q22,q22)
9897AML, 11q23 abnormalities
    Subgroup 39895AML, with multilineage dysplasia1370.06(0.05-0.07)0.07(0.06-0.09)0.05(0.04-0.07)
9984Refractory anemia with excess blasts in transformation (obsolete)
    Subgroup 49931Acute panmyelosis with myelofibrosis1060.05(0.04-0.06)0.05(0.04-0.07)0.04(0.03-0.05)
Myeloproliferative neoplasms74743.34(3.26-3.41)3.50(3.39-3.62)3.18(3.08-3.28)
    CML9863CML, NOS24681.10(1.06-1.15)1.23(1.17-1.30)0.98(0.92-1.04)
9875Chronic myelogenous leukemia, BCR/ABL positive
    Other myeloproliferative neoplasms50062.24(2.17-2.30)2.27(2.19-2.36)2.20(2.11-2.29)
        Subgroup 19950Polycythemia vera34311.53(1.48-1.58)1.57(1.49-1.64)1.50(1.43-1.57)
9961Myelosclerosis with myeloid metaplasia
9962Essential thrombocythemia
9963Chronic neutrophilic leukemia
9964Hypereosinophilic syndrome
        Subgroup 29960Chronic myeloproliferative disease, NOS15460.69(0.66-0.73)0.69(0.64-0.74)0.69(0.64-0.74)
Myelodysplastic syndrome40741.82(1.76-1.88)2.03(1.95-2.12)1.62(1.54-1.69)
9980Refractory anemia
9982Refractory anemia with sideroblasts
9983Refractory anemia with excess blasts
9985Refractory cytopenia with multilineage dysplasia
9986Myelodysplastic syndrome 5q deletion
9989Myelodysplastic syndrome, NOS
Myelodysplastic/myeloproliferative neoplasms7760.35(0.32-0.37)0.42(0.38-0.46)0.28(0.25-0.31)
9945Chronic myelomonocytic leukemia
9876Atypical CML, BCR/ABL-1 negative
9946Juvenile myelomonocytic leukemia
9975Myelodysplastic/myeloproliferative neoplasm, unclassifiable
Unknown myeloid neoplasms13650.61(0.58-0.64)0.66(0.61-0.71)0.56(0.52-0.61)
    Leukemia, NOS9800Leukemia, NOS10100.45(0.42-0.48)0.48(0.44-0.53)0.42(0.38-0.46)
9801Acute leukemia, NOS
9805Acute leukemia, ambiguous lineage
    Myeloid leukemia, NOS9860Myeloid leukemia, NOS3550.16(0.14-0.18)0.17(0.15-0.20)0.14(0.12-0.17)
All myeloid malignancies21 7969.73(9.60-9.86)10.51(10.32-10.70)8.99(8.82-9.17)
  • * Eight cases of therapy-related AML, NOS, and therapy-related myelodysplastic syndrome, NOS (ICD-O-3 codes 9920 and 9987, respectively) not shown in Table 3 were included with acute myeloid leukemia.

  • Twenty-nine cases of mastocytoma NOS/mast cell sarcoma, malignant mastocytosis, and mast cell leukemia (ICD-O-3 codes 9740, 9741, and 9742, respectively) not shown in Table 3 were included with other myeloproliferative neoplasms.