Table 3

Multivariable models with waking oxygen saturation

Dependent variable/independent and confounding variablesParameter estimateStandardized coefficientP
LV mass index, g/m2.7 (R2 = 0.62, P < .001)
    Waking oxygen saturation, percentage−1.6−0.57< .001
    Age, y−0.78−0.28.02
    Arousal index0.650.24.04
    Systolic blood pressure percentile0.10.23.05
LV diastolic dimension Z-score (R2 = 0.72, P < .001)
    Sleep maintenance efficiency, percentage−0.07−0.58< .001
    Waking oxygen saturation, percentage−0.13−0.42< .001
    Heart rate−0.04−0.4.006
    Arousal index0.090.28.02
    Systolic blood pressure percentile0.020.31.02
    Hemoglobin, g/dL−0.3−0.28.03
LV E/E′ (R2 = 0.31, P = .002)
    Waking oxygen saturation, percentage−0.31−0.56< .001
    Oxygen desaturation index−0.05−0.32.04
  • Multivariable models of LV diastolic dimension Z-score and LV mass index with waking oxygen saturation, sleep variables, and confounding independent variables for 44 study subjects. Sleep variables as potential independent variables: arousal index, sleep maintenance efficiency, OAHI at 3% desaturation, and oxygen desaturation index. Potential confounding variables evaluated: hemoglobin, LDH, arginine-ornithine ratio, age, heart rate, systolic and diastolic blood pressure percentiles, and body mass index percentile.