Table 8

Grade of severity and management of patients with ITP

Bleeding/quality of lifeManagement approach
Grade 1. Minor bleeding, few petechiae (≤ 100 total) and/or ≤ 5 small bruises (≤ 3-cm diameter); no mucosal bleedingConsent for observation
Grade 2. Mild bleeding, many petechiae (> 100 total) and/or > 5 large bruises (> 3-cm diameter); no mucosal bleedingConsent for observation or for treatment in selected children
Grade 3. Moderate bleeding, overt mucosal bleeding, troublesome lifestyleIntervention to reach grade 1/2 in selected children
Grade 4. Mucosal bleeding or suspected internal hemorrhageIntervention
  • Modified from Buchanan and Adix181; Bolton-Maggs and Moon174; Imbach et al.171