Table 2

Contents of neutrophil granule subsets

Secretory vesiclesTertiary granulesSecondary granulesPrimary granules
ReleasePMN-EC interactionPenetration of basement membraneExtravascular tissueExtravascular tissue
Receptors and membrane-bound proteinsFPR, CD14, CD16 β2-integrins, proteinase-3FPR, β2-integrins, TNF receptorFPR, β2-integrins, laminin receptor, CD66, CD67CD63, CD68
Proteins released into the surroundingAzurocidin, albuminMMP-9, lysozyme, arginaseCollagenase, LL-37, lysozyme, lactoferrinAzurocidin, HNP1-3, cathepsin G, elastase, MPO, proteinase-3