Table 1.

Patient characteristics

cGVHDNo cGVHDP
Number 30 27 NA
Median age, y 44 36 .22
Sex .43
Male 17 12
Female 13 15
Diagnosis NA
Chronic myeloid leukemia 11 5
Acute lymphoblastic leukemia 3 1
Acute myeloid leukemia 8 7
Myelodysplastic syndrome 7 5
Multiple myeloma 1 0
Non-Hodgkin lymphoma 0 5
Hodgkin lymphoma 0 3
Aplastic anemia 0 1
Conditioning regimen .09
Myeloablative 29 22
Nonmyeloablative 1 5
Stem cell source <.001
Bone marrow 26 10
Peripheral blood 4 17
Donor .06
Related 13 19
Unrelated 17 8
HLA .09
Matched 25 25
Mismatched 5 2
Sex match, patient/donor NA
M/M 7 6
M/F 10 6
F/M 4 4
F/F 9 11
Acute GVHD grade II to IV .01
No 14 22
Yes 16 5
Median time after transplantation
(range), mo 24 (7-124) 19 (5-127) .08
Immunosuppressive drugs 29 12 <.001
cGVHD grade NA
Mild 23 NA
Moderate 6 NA
Severe 1 NA
  • NA indicates not applicable.