Table 2.

Flow cytometry analysis of PBMCs from patients 10 and 11 at 24 hours after infection with 10 MOI V-WT, PUVA-V-WT, rV-TRICOM, or PUVA-rV-TRICOM

Patient, vectorB7-1, % (MFI)ICAM-1, % (MFI)LFA-3, % (MFI)
Patient 10
   Uninfected 12.0 (22) 19.9 (31) 38.9 (30)
   V-WT 17.1 (33) 23.7 (28) 37.6 (22)
   PUVA-V-WT 23.5 (17) 17.4 (28) 41.4 (29)
   rV-TRICOM 39.9 (130) 54.9 (483) 49.6 (112)
   PUVA-rV-TRICOM 27.5 (116) 27.5 (125) 39.5 (39)
Patient 11
   Uninfected 18.1 (31) 81.1 (62) 48.4 (32)
   V-WT 15.4 (34) 76.7 (37) 36.1 (20)
   PUVA-V-WT 13.6 (43) 75.7 (29) 45.0 (19)
   rV-TRICOM 52.8 (237) 96.3 (1055) 75.1 (168)
   PUVA-rV-TRICOM 38.3 (129) 89.1 (414) 51.9 (73)
  • Percentages are for cells that were positive for CD19 and each costimulatory molecule (B7-1, ICAM-1, and LFA-3). MFI values are for the expression of each costimulatory molecule.