Table 2.

Expression of lineage-specific and differentiation markers on CD45+ cells harvested from NOD/SCID bone marrow

Patient no./recipient% human leukocytes CD45% B lineage% progenitors CD34% FISH-positive
CD10CD19CD22
CD34+/CD10-
      9/1° 35 83 87 56 88
      9/2° 46 85 90 58 83
   10/1° 28 88 92 80 72 89
   10/2° 25 92 90 77 80 90
   43/1° 6 87 96 60 93
   43/2° 2 91 92 58 89
   47/1° 20 84 88 80 100
   47/2° 28 87 80 73 100
CD34+/CD19-
      9/1° 12 86 91 63 85
      9/2° 15 80 83 55 83
   10/1° 79 92 95 84 90 91
   10/2° 82 90 97 80 86 100
   25/1° 95 78 80 75 79
   25/2° 95 82 85 80 75
  • 1° indicates primary NOD/SCID recipient; 2°, secondary NOD/SCID recipient; and —, not tested.