Table 4.

Change of cell number of lymphocyte subpopulations after pamidronate/IL-2 infusion of patients from cohort B

Increase γδ T cells, % mean (range)
Dose level, IL-2 IU/m2 Patients, n Increase αβ T cells, % mean (range) Increase NK cells, % mean (range) Vδ1 (range) Vγ9δ2 (range)
0.25 × 106 3 47 (−3-82) 44 (42-152) 64 (0-114) 0 (0)
0.5 × 106 3 19 (11-23) 122 (19-136) 0 (−3-0) 128 (24-257)
1 × 106 4 35 (7-70) 30 (0-98) 0 (0-36) 89 (−15-210)
2 × 106 3 12 (−5-14) 37 (26-71) 0 (0-8) 57 (21-95)
  • Results represent means of increase in absolute cell numbers on day 7.