Table 1.

Results from patients with thrombocytopenia

CasePlatelet count (× 109/L)Direct PIFT T/C ratio*OD values
Direct MAIPAIndirect MAIPA
ControlPatientControlPatient
123.60.131.850.120.151-153
266.80.090.230.010.10
3722.8ntnt0.010.21
412ntntnt0.010.21
5358.80.011.630.020.08
6583.90.131.070.120.29
7601.90.03> 3.50.020.26
8napositiventnt0.230.60
9napositiventnt0.020.18
10nanantnt0.090.151-153
0.091-159 0.541-159
  • * Flow cytometry test results as a ratio of the test result (T) compared with the control (C). Samples 8 and 9 were tested by microscopy.

  • Results from control healthy donor platelets and patient's own platelets tested in parallel, using SW16 anti-GPV as capture mAb.

  • Average result from testing at least 3 cells previously incubated with the blood group AB control sera and patient's serum tested in parallel, using SW16 anti-GPV as capture mAb.

  • F1-153 Result not above cut-off of twice the control result.

  • F1-159 Autoantibodies were eluted from the patient's platelets and tested by MAIPA.

  • na, not available, archive samples referred to in the text; nt, not tested.