Table 2.

Cyclosporine and methotrexate levels

Time after transplantationIL-1RaPlaceboP
Cyclosporine trough (mean ± SD μg/L)
Week 1225 ± 78 (n = 90)235 ± 81 (n = 89).37
Week 2273 ± 82 (n = 90)268 ± 87 (n = 89).66
Week 3259 ± 74 (n = 91)283 ± 94 (n = 86).07
Week 4258 ± 90 (n = 85)265 ± 101 (n = 86).64
Week 5256 ± 96 (n = 82)270 ± 129 (n = 79).44
Prescribed dose administered, %
Day 1 9999.17
Day 310098.17
Day 6 9998.40
Day 11 8677.09