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First Edition

August 22, 2019

August 21, 2019

August 20, 2019

August 16, 2019

  • Genomic and Transcriptomic Association Studies Identify 16 Novel Susceptibility Loci for Venous Thromboembolism
    Sara Lindstrom, Lu Wang, Erin N. Smith, William Gordon, Astrid van Hylckama Vlieg, Mariza de Andrade, Jennifer A. Brody, Jack W. Pattee, Jeffrey Haessler, Ben M. Brumpton, Daniel I. Chasman, Pierre Suchon, Ming-Huei Chen, Constance Turman, Marine Germain, Kerri L. Wiggins, James MacDonald, Sigrid K. Braekkan, Sebastian M. Armasu, Nathan Pankratz, Rebecca D. Jackson, Jonas B. Nielsen, Franco Giulianini, Marja K. Puurunen, Manal Ibrahim, Susan R. Heckbert, Scott M. Damrauer, Pradeep Natarajan, Derek Klarin, Paul S. de Vries, Maria Sabater-Lleal, Jennifer E. Huffman, Theo K. Bammler, Kelly A. Frazer, Bryan M. McCauley, Kent Taylor, James S. Pankow, Alexander P. Reiner, Maiken E. Gabrielsen, Jean-François Deleuze, Chris J. O'Donnell, Jihye Kim, Barbara McKnight, Peter Kraft, John-Bjarne Hansen, Frits R. Rosendaal, John A. Heit, Bruce M. Psaty, Weihong Tang, Charles Kooperberg, Kristian Hveem, Paul M. Ridker, Pierre-Emmanuel Morange, Andrew D. Johnson, Christopher Kabrhel, David-Alexandre Trégouët and Nicholas L. Smith

August 15, 2019

August 13, 2019

August 08, 2019

August 06, 2019

August 05, 2019

  • Recurrent somatic JAK3 mutations in NK-cell enteropathy
    Wenbin Xiao, Gaurav K Gupta, Jinjuan Yao, Yoon J Jang, Liqiang Xi, Jeeyeon Baik, Allison Sigler, Anita Kumar, Alison J Moskowitz, Maria E Arcila, Mark Raffeld, Stefania Pittaluga, Ahmet Dogan and Elaine S Jaffe
  • Targeting Protease Nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia
    Karen Aymonnier, Charlotte Kawecki, Laurence Venisse, Yacine Boulaftali, Olivier D. Christophe, Peter J. Lenting, Véronique Arocas, Emmanuelle de Raucourt, Cécile V. Denis and Marie-Christine Bouton
  • Targeted Inhibition of CD47-SIRPα Requires Fc-FcγR Interactions to Maximize Activity in T-cell Lymphomas
    Salvia Jain, Alexandria Van Scoyk, Elizabeth A. Morgan, Andrew Matthews, Kristen Stevenson, Gail Newton, Foster Powers, Anu Autio, Abner Louissaint Jr., Guillemette Pontini, Jon C. Aster, Francis W. Luscinskas and David M. Weinstock
  • PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation
    Zhihong Ren, Jeong Hyun Ahn, Hequn Liu, Yi-Hsuan Tsai, Natarajan V. Bhanu, Brian Koss, David F. Allison, Anqi Ma, Aaron J. Storey, Ping Wang, Samuel G. Mackintosh, Ricky D. Edmondson, Richard W.J. Groen, Anton C. Martens, Benjamin A. Garcia, Alan J. Tackett, Jian Jin, Ling Cai, Deyou Zheng and Gang Greg Wang
  • Discovery of a CD10 negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs
    Sorcha O'Byrne, Natalina Elliott, Siobhan Rice, Gemma Buck, Nicholas Fordham, Catherine Garnett, Laura Godfrey, Nicholas T. Crump, Gary Wright, Sarah Inglott, Peng Hua, Beth Psaila, Benjamin Povinelli, David J.H.F. Knapp, Antonio Agraz-Doblas, Clara Bueno, Ignacio Varela, Phillip Bennett, Hashem Koohy, Suzanne M. Watt, Anastasios Karadimitris, Adam J. Mead, Phillip Ancliff, Paresh Vyas, Pablo Menendez, Thomas A. Milne, Irene Roberts and Anindita Roy

July 31, 2019

  • Design and characterization of α1-antitrypsin variants for treatment of contact system-driven thromboinflammation
    Steven de Maat, Wariya Sanrattana, Reiner K. Mailer, Naomi M.J. Parr, Martin Hessing, Robert M. Koetsier, Joost C.M. Meijers, Gerard Pasterkamp, Thomas Renné and Coen Maas
  • Prospective isolation of non-hematopoietic cells of the niche and their differential molecular interactions with HSCs
    Nicole Mende, Adrien Jolly, Gulce I. Percin, Marko Günther, Maria Rostovskaya, Shyam M. Krishnan, Robert A. J. Oostendorp, Andreas Dahl, Konstantinos Anastassiadis, Thomas Höfer and Claudia Waskow
  • Genomic landscape of Neutrophilic Leukemias of Ambiguous Diagnosis
    Haijiao Zhang, Beth Wilmot, Daniel Bottomly, Kim-Hien T. Dao, Emily Stevens, Christopher A. Eide, Vishesh Khanna, Angela Rofelty, Samantha Savage, Anna Reister-Schultz, Nicola Long, Libbey White, Amy Carlos, Rachel Ann Henson, Chenwei Lin, Robert Searles, Robert H. Collins, Daniel J. DeAngelo, Michael W. Deininger, Tamara Dunn, Hein Than, Marlise R. Luskin, Bruno C. Medeiros, Stephen T. Oh, Daniel A. Pollyea, David P. Steensma, Richard M. Stone, Brian J. Druker, Shannon K. McWeeney, Julia E. Maxson, Jason R. Gotlib and Jeffrey W. Tyner
  • L-selectin shedding affects bacterial clearance in the lung - a new regulatory pathway for integrin-outside-in signaling
    Anika Cappenberg, Andreas Margraf, Katharina Thomas, Bernadette Bardel, Dylan A. McCreedy, Veerle Van Marck, Alexander Mellmann, Clifford A. Lowell and Alexander Zarbock
  • High frequency of inactivating tetraspanin CD37 mutations in diffuse large B-cell lymphoma at immune-privileged sites
    Suraya Elfrink, Charlotte M de Winde, Michiel van den Brand, Madeleine Rosa Berendsen, Margaretha Roemer, Frank Arnold, Luuk Janssen, Alie van der Schaaf, Erik Jansen, Patricia JTA Groenen, Astrid Eijkelenboom, Wendy B.C. Stevens, Corine J Hess, Johan HJM Han van Krieken, Joost S Vermaat, Arjen Cleven, Ruben AL de Groen, Viviana Neviani, Daphne De Jong, Sjoerd van Deventer, Blanca Scheijen and Annemiek van Spriel
  • LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis
    Tatsuya Morishima, Ann-Christin Krahl, Masoud Nasri, Yun Xu, Narges Aghaallaei, Betül Findik, Maksim Klimiankou, Malte Ritter, Marcus D. Hartmann, Christian Johannes Gloeckner, Sylwia Stefańczyk, Christian Lindner, Benedikt Oswald, Regine Bernhard, Karin Hähnel, Ursula Hermanutz-Klein, Martin Ebinger, Rupert Handgretinger, Nicolas Casadei, Karl Welte, Maya Andre, Patrick Müller, Baubak Bajoghli and Julia Skokowa
  • Sepsis Alters the Transcriptional and Translational Landscape of Human and Murine Platelets
    Elizabeth A Middleton, Jesse W Rowley, Robert A. Campbell, Colin K Grissom, Samuel M Brown, Sarah J Beesley, Hansjörg Schwertz, Yasuhiro Kosaka, Bhanu Kanth Manne, Krystin Krauel, Neal D. Tolley, Alicia S Eustes, Li Guo, Robert Paine III, Estelle Harris, Guy A. Zimmerman, Andrew S Weyrich and Matthew T. Rondina

July 26, 2019

  • Phase 1 study of selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL
    Constantine Si Lun Tam, Judith Trotman, Stephen Opat, Jan A Burger, Gavin Cull, David J Gottlieb, Rosemary Anne Harrup, Patrick Johnston, Paula Marlton, Javier Munoz, John F. Seymour, David R Simpson, Alessandra Tedeschi, Rebecca Elstrom, Yiling Yu, Zhiyu Tang, Lynn Han, Jane Huang, William Novotny, Lai Wang and Andrew W. Roberts
  • Effect of donor, component and recipient characteristics on hemoglobin increments following red blood cell transfusion
    Nareg Roubinian, Colleen Plimier, Jennifer Woo, Catherine Lee, Roberta Bruhn, Vincent Liu, Gabriel Jorge Escobar, Steven H Kleinman, Darrell J Triulzi, Edward L. Murphy and Michael P Busch
  • Genetic determinants of VWF clearance and FVIII-binding modify FVIII pharmacokinetics in pediatric hemophilia A patients
    Laura L. Swystun, Kenichi Ogiwara, Orla Rawley, Christine Brown, Ilinca Georgescu, Wilma Hopman, Veerle Labarque, Christoph Male, Katharina Thom, Victor S. Blanchette, Manuel Carcao and David Lillicrap
  • Impact of Concurrent Indolent Lymphoma on the Clinical Outcome of Newly Diagnosed Diffuse Large B-Cell Lymphoma
    Yucai Wang, Brian K. Link, Thomas E. Witzig, Matthew J. Maurer, Cristine Allmer, Rebecca L. King, Andrew L. Feldman, Thomas M. Habermann, Stephen M. Ansell, Susan L. Slager, James R. Cerhan and Grzegorz S. Nowakowski
  • Inherited genetic susceptibility of acute lymphoblastic leukemia in Down syndrome
    Austin L. Brown, Adam J. de Smith, Vincent U. Gant, Wenjian Yang, Michael E. Scheurer, Kyle M. Walsh, Jonathan M. Chernus, Noah A. Kallsen, Shanna A. Peyton, Gareth E. Davies, Erik A. Ehli, Naomi Winick, Nyla A. Heerema, Andrew J. Carroll, Michael J. Borowitz, Brent L. Wood, Wiiliam L. Carroll, Elizabeth A. Raetz, Eleanor Feingold, Meenakshi Devidas, Lisa F. Barcellos, Helen M. Hansen, Libby Morimoto, Alice Y. Kang, Ivan Smirnov, Jasmine Healy, Caroline Laverdière, Daniel Sinnett, Jeffrey W. Taub, Jillian M. Birch, Pamela Thompson, Logan G. Spector, Maria S. Pombo-de-Oliveira, Andrew T. DeWan, Charles G. Mullighan, Stephen P. Hunger, Ching-Hon Pui, Mignon L. Loh MD, Michael E. Zwick, Catherine Metayer, Xiaomei Ma, Beth A. Mueller, Stephanie L. Sherman, Joseph L. Wiemels, Mary V. Relling, Jun J. Yang, Philip J. Lupo and Karen R. Rabin

July 24, 2019

  • Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness
    Umair Munawar, Leo Rasche, Nicole Müller, Cornelia Vogt, Matteo Da-Via, Larissa Haertle, Panagiota Arampatzi, Sascha Dietrich, Markus Roth, Andoni Garitano-Trojaola, Maximilian Johannes Steinhardt, Susanne Strifler, Miguel Gallardo, Joaquin Martinez-Lopez, Ralf C. Bargou, Tobias Heckel, Hermann Einsele, Thorsten Stühmer, K. Martin Kortüm and Santiago Barrio

July 22, 2019

  • Antibiotics inhibit tumor and disease activity in cutaneous T cell lymphoma
    Lise M. Lindahl, Andreas Willerslev-Olsen, Lise M. R. Gjerdrum, Pia R. Nielsen, Edda Blümel, Anne H. Rittig, Pamela Celis, Bjorn Herpers, Jürgen C. Becker, Birgitte Stausbøl-Grøn, Mariusz A. Wasik, Maria Gluud, Simon Fredholm, Terkild B. Buus, Claus Johansen, Claudia Nastasi, Lukas Peiffer, Linda Kubat, Michael Bzorek, Jens O. Eriksen, Thorbjørn Krejsgaard, Charlotte M. Bonefeld, Carsten Geisler, Tomas Mustelin, Erik Langhoff, Michael Givskov, Anders Woetmann, Mogens Kilian, Thomas Litman, Lars Iversen and Niels Odum
  • Adjuvant low-dose rituximab and plasma exchange for acquired TTP
    Jeffrey I. Zwicker, Joshua Muia, Leili Dolatshahi, Lisa A. Westfield, Patricia Nieters, Anita Rodrigues, Ayad Hamdan, Ana G. Antun, Ara Metjian and J. Evan Evan Sadler
  • Five-Year Follow-up of SWOG S0816: Limitations and Values of a PET-Adapted Approach for Stage III/IV Hodgkin Lymphoma
    Deborah M Stephens, Hongli Li, Heiko Schöder, David J. Straus, Craig H. Moskowitz, Michael Leblanc, Lisa M Rimsza, Nancy L Bartlett, Andrew M Evens, Ann S. LaCasce, Paul M. Barr, Michael V Knopp, Eric Hsi, John P Leonard, Brad Kahl, Sonali M Smith and Jonathan W Friedberg
  • Ibrutinib plus lenalidomide and rituximab has promising activity in relapsed/refractory non-germinal center B-cell DLBCL
    Andre Goy, Radhakrishnan Ramchandren, Nilanjan Ghosh, Javier Munoz, David S. Morgan, Nam H. Dang, Mark Knapp, Maria Delioukina, Edwin Kingsley, Jerry Ping, Darrin M. Beaupre, Jutta K. Neuenburg and Jia Ruan

July 18, 2019

  • Tisagenlecleucel CAR-T Cell Therapy in Secondary CNS Lymphoma
    Matthew J. Frigault, Jorg Dietrich, Maria Martinez-Lage, Mark Leick, Bryan D. Choi, Zachariah DeFilipp, Yi-Bin Chen, Jeremy Abramson, Jennifer Crombie, Philippe Armand, Lakshmi Nayak, Christopher Panzini, Lauren S. Riley, Kathleen Gallagher and Marcela Maus

July 16, 2019

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