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Tumor-educated platelets

Sjors G.J.G. In 't Veld and Thomas Wurdinger

Abstract

Liquid biopsies have been considered the holy grail towards achieving effective cancer management, with blood tests offering a minimally invasive, safe, and sensitive alternative or complementary approach for tissue biopsies. Currently, blood-based liquid biopsy measurements focus on evaluation of biomarker types, including circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), extracellular vesicles (EVs; exosomes, oncosomes), and tumor-educated platelets (TEPs). Despite the potential of individual techniques, each has its own advantages and disadvantages. Here we provide further insight into TEPs.

  • Submitted December 11, 2018.
  • Accepted February 26, 2019.