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A gene-based recessive diplotype exome scan discovers FGF6, a novel hepcidin-regulating iron metabolism gene

Shicheng Guo, Shuai Jiang, Narendranath Epperla, Yanyun Ma, Mehdi Maadooliat, Zhan Ye, Brent Olson, Minghua Wang, Terrie Kitchner, Jeffrey Joyce, Robert Strenn, Joseph J. Mazza, Jennifer K. Meece, Wenyu Wu, Li Jin, Judith A. Smith, Jiucun Wang and Steven J. Schrodi

Article Information

PubMed 

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Online ISSN 
History 
  • Submitted October 10, 2018
  • Accepted February 20, 2019
  • Published online February 27, 2019.


Contributors 
  • Shicheng Guo, 1 Center for Human Genetics, Marshfield Clinic Research Institute, Marshfield, WI, United States;
  • Shuai Jiang, 2 State Key Lab. of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China;
  • Narendranath Epperla, 3 Division of Hematology, The Ohio State University, Columbus, OH, United States;
  • Yanyun Ma, 4 Human Phenome Institute, Fudan University, Shanghai, China;
  • Mehdi Maadooliat, 5 Department of Mathematics, Statistics and Computer Science, Marquette University, Milwaukee, WI, United States;
  • Zhan Ye, 6 Biomedical Informatics Research Center, Marshfield Clinic Research Institute, Marshfield, WI, United States;
  • Brent Olson, 6 Biomedical Informatics Research Center, Marshfield Clinic Research Institute, Marshfield, WI, United States;
  • Minghua Wang, 7 Department of Biochemistry and Molecular Biology, Medical College, Soochow University, Suzhou, China;
  • Terrie Kitchner, 1 Center for Human Genetics, Marshfield Clinic Research Institute, Marshfield, WI, United States;
  • Jeffrey Joyce, 1 Center for Human Genetics, Marshfield Clinic Research Institute, Marshfield, WI, United States;
  • Robert Strenn, 6 Biomedical Informatics Research Center, Marshfield Clinic Research Institute, Marshfield, WI, United States;
  • Joseph J. Mazza, 8 Clinical Research Center, Marshfield Clinic Research Institute, Marshfield, WI, United States;
  • Jennifer K. Meece, 9 Integrated Research and Development Laboratory, Marshfield Clinic Research Institute, Marshfield, WI, United States;
  • Wenyu Wu, 10 Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China;
  • Li Jin, 2 State Key Lab. of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China;
  • Judith A. Smith, 11 Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, United States;
  • Jiucun Wang, 12 Institute of Rheumatology, Immunology and Allergy, Fudan University, Shanghai, China
  • Steven J. Schrodi, 1 Center for Human Genetics, Marshfield Clinic Research Institute, Marshfield, WI, United States;

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