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Mutant calreticulin knock-in mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage

Juan Li, Daniel Prins, Hyun Jung Park, Jacob Grinfeld, Carlos Gonzalez-Arias, Stephen Loughran, Oliver M. Dovey, Thorsten Klampfl, Cavan Bennett, Tina L. Hamilton, Dean C. Pask, Rachel Sneade, Matthew Williams, Juliet Aungier, Cedric Ghevaert, George S. Vassiliou, David G. Kent and Anthony R. Green

Article Information

PubMed 

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History 
  • Submitted September 13, 2017
  • Accepted December 15, 2017
  • Published online December 27, 2017.

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Contributors 
  • Juan Li, 1 Cambridge Institute for Medical Research and Wellcome Trust/MRC Stem Cell Institute, University of Cambridge, United Kingdom;
  • Daniel Prins, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Hyun Jung Park, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Jacob Grinfeld, 3 Department of Haematology, Addenbrooke's Hospital, Cambridge, United Kingdom;
  • Carlos Gonzalez-Arias, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Stephen Loughran, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Oliver M. Dovey, 4 Welcome Trust Sanger Institute, Cambridge, United Kingdom;
  • Thorsten Klampfl, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Cavan Bennett, 5 NHS Blood and Transplant, Cambridge, United Kingdom
  • Tina L. Hamilton, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Dean C. Pask, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Rachel Sneade, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Matthew Williams, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Juliet Aungier, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Cedric Ghevaert, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • George S. Vassiliou, 4 Welcome Trust Sanger Institute, Cambridge, United Kingdom;
  • David G. Kent, 2 Department of Haematology, University of Cambridge, United Kingdom;
  • Anthony R. Green, 2 Department of Haematology, University of Cambridge, United Kingdom;

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