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Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin

Sharraya Aschemeyer, Bo Qiao, Deborah Stefanova, Erika V. Valore, Albert C. Sek, T. Alex Ruwe, Kyle R. Vieth, Grace Jung, Carla Casu, Stefano Rivella, Mika Jormakka, Bryan Mackenzie, Tomas Ganz and Elizabeta Nemeth

Article Information

PubMed 

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History 
  • Submitted May 23, 2017
  • Accepted November 30, 2017
  • Published online December 13, 2017.


Contributors 
  • Sharraya Aschemeyer, 1 Molecular Biology Interdepartmental Doctoral Program, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;
  • Bo Qiao, 2 Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;
  • Deborah Stefanova, 3 Department of Molecular, Cellular, and Integrative Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;
  • Erika V. Valore, 2 Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;
  • Albert C. Sek, 3 Department of Molecular, Cellular, and Integrative Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;
  • T. Alex Ruwe, 4 Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, United States;
  • Kyle R. Vieth, 4 Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, United States;
  • Grace Jung, 2 Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;
  • Carla Casu, 5 Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States;
  • Stefano Rivella, 5 Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States;
  • Mika Jormakka, 6 Structural Biology Program, Centenary Institute, University of Sydney, Sydney, NSW, Australia;
  • Bryan Mackenzie, 4 Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, United States;
  • Tomas Ganz, 7 Department of Pathology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States
  • Elizabeta Nemeth, 2 Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States;

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