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LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis

Sara El Ashkar, Juerg Schwaller, Tim Pieters, Steven Goossens, Jonas Demeulemeester, Frauke Christ, Siska Van Belle, Sabine Juge, Nancy Boeckx, Alan Engelman, Pieter Van Vlierberghe, Zeger Debyser and Jan De Rijck

Article Information

PubMed 

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History 
  • Submitted May 30, 2017
  • Accepted October 20, 2017
  • Published online October 30, 2017.


Contributors 
  • Sara El Ashkar, 1 Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium;
  • Juerg Schwaller, 2 Department of Biomedicine, University Children's Hospital (UKBB), University of Basel, Switzerland;
  • Tim Pieters, 3 Center for Medical Genetics, Ghent University, Ghent, Belgium;
  • Steven Goossens, 4 Cancer Research Institute Ghent (CRIG), Ghent, Belgium;
  • Jonas Demeulemeester, 1 Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium;
  • Frauke Christ, 1 Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium;
  • Siska Van Belle, 1 Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium;
  • Sabine Juge, 2 Department of Biomedicine, University Children's Hospital (UKBB), University of Basel, Switzerland;
  • Nancy Boeckx, 5 Department of Oncology, KU Leuven, Leuven, Belgium;
  • Alan Engelman, 6 Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States
  • Pieter Van Vlierberghe, 3 Center for Medical Genetics, Ghent University, Ghent, Belgium;
  • Zeger Debyser, 1 Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium;
  • Jan De Rijck, 1 Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium;

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