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CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells

David K. Edwards V, Kevin Watanabe-Smith, Angela Rofelty, Alisa Damnernsawad, Ted Laderas, Adam Lamble, Evan F. Lind, Andy Kaempf, Motomi Mori, Mara Rosenberg, Amanda d’Almeida, Nicola Long, Anupriya Agarwal, David Tyler Sweeney, Marc Loriaux, Shannon K. McWeeney and Jeffrey W. Tyner

Article Information

Citation 
vol. 133 no. 6 588-599
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted March 27, 2018
  • Accepted November 9, 2018
  • Published online February 7, 2019.

Article Versions


Contributors 
  • David K. Edwards V, 1Department of Cell, Developmental & Cancer Biology, Knight Cancer Institute,
  • Kevin Watanabe-Smith, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Angela Rofelty, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Alisa Damnernsawad, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Ted Laderas, 3Department of Medical Informatics and Clinical Epidemiology, and
  • Adam Lamble, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Evan F. Lind, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Andy Kaempf, 4Biostatistics Shared Resource, Knight Cancer Institute, Oregon Health & Science University, Portland, OR; and
  • Motomi Mori, 4Biostatistics Shared Resource, Knight Cancer Institute, Oregon Health & Science University, Portland, OR; and 5School of Public Health, Oregon Health & Science University–Portland State University, Portland, OR
  • Mara Rosenberg, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Amanda d’Almeida, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Nicola Long, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Anupriya Agarwal, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • David Tyler Sweeney, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Marc Loriaux, 2Division of Hematology and Medical Oncology, Knight Cancer Institute,
  • Shannon K. McWeeney, 3Department of Medical Informatics and Clinical Epidemiology, and
  • Jeffrey W. Tyner, 1Department of Cell, Developmental & Cancer Biology, Knight Cancer Institute,

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