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Ravulizumab (ALXN1210) vs eculizumab in C5-inhibitor–experienced adult patients with PNH: the 302 study

Austin G. Kulasekararaj, Anita Hill, Scott T. Rottinghaus, Saskia Langemeijer, Richard Wells, F. Ataulfo Gonzalez-Fernandez, Anna Gaya, Jong Wook Lee, Emilio Ojeda Gutierrez, Caroline I. Piatek, Jeff Szer, Antonio Risitano, Shinji Nakao, Eric Bachman, Lori Shafner, Andrew I. Damokosh, Stephan Ortiz, Alexander Röth and Regis Peffault de Latour

Article Information

Citation 
vol. 133 no. 6 540-549
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted September 26, 2018
  • Accepted November 18, 2018
  • Published online February 7, 2019.

Article Versions


Contributors 
  • Austin G. Kulasekararaj, 1Department of Haematological Medicine, King’s College Hospital, National Institute of Health Research/Wellcome King’s Clinical Research Facility, London, United Kingdom;
  • Anita Hill, 2Department of Haematology, Leeds Teaching Hospitals, Leeds, United Kingdom;
  • Scott T. Rottinghaus, 3Alexion Pharmaceuticals, Inc., Boston, MA;
  • Saskia Langemeijer, 4Radboudumc, Nijmegen, The Netherlands;
  • Richard Wells, 5Sunnybrook Health Sciences Centre, Toronto, ON, Canada;
  • F. Ataulfo Gonzalez-Fernandez, 6Hospital Clinico Universitario San Carlos, Department of Hematology, The Clínic Institute of Haematological and Oncological Diseases, Madrid, Spain;
  • Anna Gaya, 7Hospital Clínic de Barcelona, Barcelona, Spain;
  • Jong Wook Lee, 8Department of Hematology, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Republic of Korea;
  • Emilio Ojeda Gutierrez, 9Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain;
  • Caroline I. Piatek, 10Jane Anne Nohl Division of Hematology, Keck School of Medicine of USC, Los Angeles, CA;
  • Jeff Szer, 11Clinical Haematology, Royal Melbourne Hospital, Melbourne, VIC, Australia;
  • Antonio Risitano, 12Hematology, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy;
  • Shinji Nakao, 13Haematology/Respiratory Medicine, Faculty of Medicine, Institute of Medical Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan;
  • Eric Bachman, 3Alexion Pharmaceuticals, Inc., Boston, MA;
  • Lori Shafner, 3Alexion Pharmaceuticals, Inc., Boston, MA;
  • Andrew I. Damokosh, 3Alexion Pharmaceuticals, Inc., Boston, MA;
  • Stephan Ortiz, 3Alexion Pharmaceuticals, Inc., Boston, MA;
  • Alexander Röth, 14Department of Hematology, West German Cancer Center, University Hospital Essen, Essen, Germany;
  • Regis Peffault de Latour, 15Bone Marrow Transplantation Unit, Saint Louis Hospital, Assistance Publique–Hôpitaux de Paris, Paris, France; 16French Reference Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Saint Louis Hospital and University Paris Diderot, Paris, France; and 17Severe Aplastic Anemia Working Party of the European Group for Blood and Marrow Transplantation, Leiden, The Netherlands

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