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Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

Wendy W. Pang, Agnieszka Czechowicz, Aaron C. Logan, Rashmi Bhardwaj, Jessica Poyser, Christopher Y. Park, Irving L. Weissman and Judith A. Shizuru

Article Information

Citation 
vol. 133 no. 19 2069-2078
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted June 19, 2018
  • Accepted December 18, 2018
  • Published online May 9, 2019.

Article Versions


Contributors 
  • Wendy W. Pang, 1Division of Hematology, Department of Medicine, 2Division of Blood and Marrow Transplantation, Department of Medicine, 3Institute for Stem Cell and Regenerative Medicine, 4Stanford Cancer Institute, and
  • Agnieszka Czechowicz, 3Institute for Stem Cell and Regenerative Medicine, 4Stanford Cancer Institute, and 5Department of Developmental Biology, School of Medicine, Stanford University, Stanford, CA; 6Department of Pathology, 7Department of Clinical Laboratories, and 8Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY; 9Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, School of Medicine, Stanford University, Stanford, CA; 10Department of Pathology, Stanford University Medical Center, Stanford, CA;
  • Aaron C. Logan, 11Division of Hematology and Blood and Marrow Transplantation, Department of Medicine, School of Medicine, University of California San Francisco, San Francisco, CA;
  • Rashmi Bhardwaj, 6Department of Pathology, 7Department of Clinical Laboratories, and 8Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY;
  • Jessica Poyser, 2Division of Blood and Marrow Transplantation, Department of Medicine, 3Institute for Stem Cell and Regenerative Medicine, 4Stanford Cancer Institute, and
  • Christopher Y. Park, 12Department of Pathology, School of Medicine, New York University, New York, NY; and
  • Irving L. Weissman, 3Institute for Stem Cell and Regenerative Medicine, 4Stanford Cancer Institute, and 10Department of Pathology, Stanford University Medical Center, Stanford, CA; 13Ludwig Center for Cancer Cell Research, School of Medicine, Stanford University, Stanford, CA
  • Judith A. Shizuru, 2Division of Blood and Marrow Transplantation, Department of Medicine, 3Institute for Stem Cell and Regenerative Medicine, 4Stanford Cancer Institute, and 9Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, School of Medicine, Stanford University, Stanford, CA;

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