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Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3

Robert A. Campbell, Hansjorg Schwertz, Eugenio D. Hottz, Jesse W. Rowley, Bhanu Kanth Manne, A. Valance Washington, Robert Hunter-Mellado, Neal D. Tolley, Miles Christensen, Alicia S. Eustes, Emilie Montenont, Seema Bhatlekar, Cassandra H. Ventrone, Beth D. Kirkpatrick, Kristen K. Pierce, Stephen S. Whitehead, Sean A. Diehl, Paul F. Bray, Guy A. Zimmerman, Yasuhiro Kosaka, Patricia T. Bozza, Fernando A. Bozza, Andrew S. Weyrich and Matthew T. Rondina

Article Information

Citation 
vol. 133 no. 19 2013-2026
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted September 9, 2018
  • Accepted January 22, 2019
  • Published online May 9, 2019.

Article Versions


Contributors 
  • Robert A. Campbell, 1University of Utah Molecular Medicine Program, Salt Lake City, UT; 2Department of Internal Medicine and
  • Hansjorg Schwertz, 1University of Utah Molecular Medicine Program, Salt Lake City, UT; 2Department of Internal Medicine and 3Rocky Mountain Center for Occupational and Environmental Health, University of Utah, Salt Lake City, UT;
  • Eugenio D. Hottz, 1University of Utah Molecular Medicine Program, Salt Lake City, UT; 4Instituto Nacional de Infectologia Evandro Chagas and 5Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil;
  • Jesse W. Rowley, 1University of Utah Molecular Medicine Program, Salt Lake City, UT; 2Department of Internal Medicine and
  • Bhanu Kanth Manne, 1University of Utah Molecular Medicine Program, Salt Lake City, UT;
  • A. Valance Washington, 6Department of Biology, University of Puerto Rico–Rio Piedras, San Juan, Puerto Rico; 7Department of Internal Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico;
  • Robert Hunter-Mellado, 6Department of Biology, University of Puerto Rico–Rio Piedras, San Juan, Puerto Rico; 7Department of Internal Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico;
  • Neal D. Tolley, 1University of Utah Molecular Medicine Program, Salt Lake City, UT;
  • Miles Christensen, 2Department of Internal Medicine and
  • Alicia S. Eustes, 1University of Utah Molecular Medicine Program, Salt Lake City, UT;
  • Emilie Montenont, 1University of Utah Molecular Medicine Program, Salt Lake City, UT;
  • Seema Bhatlekar, 1University of Utah Molecular Medicine Program, Salt Lake City, UT;
  • Cassandra H. Ventrone, 8Vaccine Testing Center, Department of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, VT;
  • Beth D. Kirkpatrick, 8Vaccine Testing Center, Department of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, VT;
  • Kristen K. Pierce, 8Vaccine Testing Center, Department of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, VT;
  • Stephen S. Whitehead, 9National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD;
  • Sean A. Diehl, 8Vaccine Testing Center, Department of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, VT;
  • Paul F. Bray, 1University of Utah Molecular Medicine Program, Salt Lake City, UT; 2Department of Internal Medicine and
  • Guy A. Zimmerman, 1University of Utah Molecular Medicine Program, Salt Lake City, UT; 2Department of Internal Medicine and
  • Yasuhiro Kosaka, 1University of Utah Molecular Medicine Program, Salt Lake City, UT;
  • Patricia T. Bozza, 5Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil;
  • Fernando A. Bozza, 4Instituto Nacional de Infectologia Evandro Chagas and 10Instituto D’Or de Pesquisa e Ensino, Rio de Janeiro, Brazil; and
  • Andrew S. Weyrich, 1University of Utah Molecular Medicine Program, Salt Lake City, UT; 2Department of Internal Medicine and
  • Matthew T. Rondina, 1University of Utah Molecular Medicine Program, Salt Lake City, UT; 2Department of Internal Medicine and 11Department of Internal Medicine, George E. Wahlen Veterans Affairs Medical Center and Geriatric Research, Education, and Clinical Center, Salt Lake City, UT

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