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A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease

Jo Howard, Claire Jane Hemmaway, Paul Telfer, D. Mark Layton, John Porter, Moji Awogbade, Timothy Mant, Daniel D. Gretler, Kobina Dufu, Athiwat Hutchaleelaha, Mira Patel, Vincent Siu, Sandra Dixon, Noel Landsman, Margaret Tonda and Joshua Lehrer-Graiwer

Article Information

Citation 
vol. 133 no. 17 1865-1875
PubMed 

Print ISSN 
Online ISSN 
History 
  • Submitted August 13, 2018
  • Accepted December 21, 2018
  • Published online April 25, 2019.

Article Versions


Contributors 
  • Jo Howard, 1Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom; 2Department of Haematological Medicine, King’s College London, London, United Kingdom;
  • Claire Jane Hemmaway, 3Queen’s Hospital, Romford, United Kingdom;
  • Paul Telfer, 4Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom;
  • D. Mark Layton, 5Department of Haematology, Hammersmith Hospital Campus, Imperial College London, London, United Kingdom;
  • John Porter, 6Department of Haematology, University College London, London, United Kingdom;
  • Moji Awogbade, 7King’s College Hospital NHS Foundation Trust, London, United Kingdom;
  • Timothy Mant, 1Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom; 8IQVIA, Reading, United Kingdom; 9Department of Clinical Pharmacology, Faculty of Life Sciences and Medicine, King’s College London, London, United Kingdom;
  • Daniel D. Gretler, 10Independent Drug Development Consultant, San Francisco, CA; and
  • Kobina Dufu, 11Global Blood Therapeutics, Inc, South San Francisco, CA
  • Athiwat Hutchaleelaha, 11Global Blood Therapeutics, Inc, South San Francisco, CA
  • Mira Patel, 11Global Blood Therapeutics, Inc, South San Francisco, CA
  • Vincent Siu, 11Global Blood Therapeutics, Inc, South San Francisco, CA
  • Sandra Dixon, 11Global Blood Therapeutics, Inc, South San Francisco, CA
  • Noel Landsman, 11Global Blood Therapeutics, Inc, South San Francisco, CA
  • Margaret Tonda, 11Global Blood Therapeutics, Inc, South San Francisco, CA
  • Joshua Lehrer-Graiwer, 11Global Blood Therapeutics, Inc, South San Francisco, CA

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